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Neutralizing Antibody Level After COVID-19 Vaccination

Neutralizing Antibody Level After COVID-19 Vaccination

Recruiting
20-60 years
All
Phase N/A
  • Technical (Original)
  • Simplified (AI rewritten)

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Overview

  1. serial of neutralizing antibody at 2, 4, 6, 9, 12 month after COVID-19 vaccination
  2. investigate the factors on antibody titer.

Description

  1. serial of neutralizing antibody at 2, 4, 6, 9, 12 month after COVID-19 vaccination 1) semi-quantitative measurement of neutralizing antibody at 2, 4, 6, 9, 12 month after COVID-19 vaccination 2) investigate the duration maintaining acceptable range (over 30% inhibition)
  2. investigate the factors on antibody titer at 2 month after vaccination 1) potential factors: age, sex, body weight, height, use of medication, use of antipyretics (NSAID or tyrenol), side effect of COVID-19 vaccination 2) correlation between antibody titer and potential factors
  3. Compare 4 diagnostic ELISA kit at 2 month after vaccination 1) measure neutralizung antibody using ELISA kits from 4 different companies 2) investigate correlation coefficient of antibody titer between companies

Eligibility

Inclusion Criteria:

  • healthcare works after completion of COVID-19 vaccination
  • 20-60 years
  • sign the agreement of study

Exclusion Criteria:

  • serious underlying diseases

Study details
    Covid19

NCT05083026

Kyungpook National University Hospital

27 January 2024

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