Overview
The aims of this study are: i) to assess cerebral autoregulation and autonomic control within the different phases of cardiac surgery with cardiopulmonary bypass; ii) to compare cerebral autoregulation measures derived via cerebral blood flow velocity estimated by transcranial Doppler device with simpler measurements derived from near infrared spectroscopy; iii) to develop a predictive model of postoperative cerebrovascular outcome (overt or silent stroke) based on the extracted indices.
Eligibility
Inclusion Criteria:
- age older than 18 years
- spontaneous sinus rhythm
- no pregnancy
- signed informed consent
Exclusion Criteria:
- age lower than 18 years
- absence of sinus rhythm
- autonomic disorders
- concomitant carotid intervention
- reintervention
- contraindication to MRI
- pregnancy
- impossibility of informed consent