Overview
This study is a prospective registry of patients undergoing endoscopic suturing and/or clip placement at our institution to assess the efficacy and safety of endoscopic tissue apposition.
1.1 Hypothesis: Endoscopic tissue apposition is efficacious and safe in the practice of gastrointestinal endoscopy.
1.2 Aims: To prospectively evaluate the efficacy and safety of Endoscopic Tissue Apposition in the practice of gastrointestinal endoscopy.
Eligibility
Inclusion Criteria:
- Patients>18 years of age undergoing endoscopy for any of the following indications:
Indications for Tissue Apposition:
- Closure of perforations
- Closure of full thickness defects created during endoscopic full thickness resection
- Closure of defects after endoscopic submucosal dissection and endoscopic mucosal resection
- Closure of mucosotomy after Peroral Endoscopic Myotomy (POEM)
- Stent fixation
- Closure of fistulas
- Natural Orifice Transluminal Endoscopic Surgery defect closures
- Post-bariatric surgery gastrojejunal anastomosis and gastric pouch revision (transoral outlet repair)
- Primary endoscopic sleeve gastroplasty
Exclusion Criteria:
- Patients unable or unwilling to provide consent
- Pregnant patients
- Coagulation disorders (INR >1.8, platelet <50,000)
- GI Bleeding
- Hemodynamic instability
- Enrollment in another device or drug study that may confound the results