Overview
Total parathyroidectomy with autotransplantation (TPTX+AT) and Total parathyr- oidectomy alone (TPTX) are the common surgical procedures.The purpose of the study was to compare the long-term benefits of surgery between the two groups.
Description
The trial was performed as a nonconfirmatory randomized controlled pilot trial with 200 patients on long-term dialysis with otherwise uncontrollable SHPT to generate data on the rate of recurrent disease within a 5-year follow-up period after TPTX or TPTX+AT. Parathyroid hormone (PTH) and calcium levels, recurrent or persistent hyperparathyroidism, parathyroid reoperations, morbidity, and mortality were evaluated during a 5-year follow-up.
Eligibility
Inclusion Criteria:
Severe renal secondary hyperparathyroidism
Exclusion Criteria:
Patients with diabetes a history of chronic inflammatory disease a history of malignant
tumor a history of kidney transplantation a history of neck surgery a history of alcohol
abuse a history of drug abuse inability to cooperate with the participants refusal to
participate in the study