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Diagnostic Efficacy of Metagenomic Next-generation Sequencing in Patients With Spinal Infections: A Retrospective Study

Diagnostic Efficacy of Metagenomic Next-generation Sequencing in Patients With Spinal Infections: A Retrospective Study

Recruiting
18 years and older
All
Phase N/A

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Overview

Comparing the diagnostic efficacy between traditional laboratory methods and second-generation high-throughput sequencing in patients suspected of spinal infections.

Eligibility

Inclusion Criteria:

        "Patients suspected of spinal infections, as per the American Infectious Diseases Society's
        2015 criteria for primary vertebral osteomyelitis, were identified based on their clinical
        symptoms, laboratory tests, and imaging examinations. All cases included in the study
        underwent laboratory examinations, histopathological examinations, and second-generation
        high-throughput sequencing (metagenomic sequencing)."
        Exclusion Criteria:
        "The absence of laboratory examinations, histopathological examinations, and results from
        second-generation high-throughput sequencing (metagenomic sequencing)."

Study details
    Spinal Infection
    Diagnositic Efficacy

NCT06172153

Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University

27 January 2024

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