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Comparison of the Effectiveness of Two Different Surgical Therapeutic Protocols of Peri-implantitis

Comparison of the Effectiveness of Two Different Surgical Therapeutic Protocols of Peri-implantitis

Recruiting
18-80 years
All
Phase N/A

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Overview

The purpose of the present study is to compare the 1-year clinical, radiographic and microbiological outcomes and patients' satisfaction following surgical treatment of peri-implantitis after applying two different surface modification methods. Secondarily, analysis and comparison of the microbiological results of implants diagnosed and treated for peri-implantitis with healthy implants will be performed.

Eligibility

Inclusion Criteria:

General Inclusion Criteria:

  • Participants ≥ 18 years and ≤ 80 years of age
  • Non-smokers based on the patients' self-reported smoking status, defined as patients who had never smoked or had quit smoking at least 2 years ago
  • Implants in function for more than 1 year after suprastructure connection

Inclusion Criteria for implants diagnosed with Peri-Implantitis:

  • Presence of at least one implant diagnosed with peri-implantitis defined as presence of bleeding on probing and/or suppuration, probing pocket depth ≥6 mm and ≥3 mm of detectable bone loss after initial re-modelling
  • Absence of implant mobility
    • in participants with more than one implant, the implant with the worst clinical condition will be studied.

Inclusion Criteria for implants diagnosed with Peri-Implant Health:

  • Absence of peri-implant signs of inflammation (redness, swelling)
  • Lack of bleeding on probing
  • Absence of bone loss beyond crestal bone level changes resulting from initial remodeling, which should not be ≥2 mm

Exclusion Criteria:

  • Smokers
  • Uncontrolled diabetes mellitus (HBA1c >7)
  • Treatment with bisphosphonates
  • Needing antibiotic prophylaxis
  • Currently pregnant or breast-feeding women
  • History of systemic administration of antibiotic treatment during the preceding 3 months
  • Systemic conditions that contraindicate treatment
  • Use of medications known to induce gingival hyperplasia

Study details
    Peri-Implantitis
    Peri-Implant Health

NCT05899933

National and Kapodistrian University of Athens

27 January 2024

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