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Valuation in Depressed Mood, Anhedonia, and Anxiety

Valuation in Depressed Mood, Anhedonia, and Anxiety

Recruiting
25-50 years
All
Phase N/A

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Overview

This study examines how people respond to rewards and losses, and the extent to which these responses are linked or distinct among people experiencing depressed mood, anhedonia, and/or anxiety.

Description

This study tests relationships among neural and behavioral valuation mechanisms, and how these mechanisms change (or not) over time, with task instructions, and following cognitive behavior therapy.

Eligibility

Inclusion Criteria:

  • mood, anxiety, or anhedonia symptoms that affect functioning; fluent in English; able to see computer display; able to perform simple computer games.

Exclusion Criteria:

  • history of seizure disorder, stroke, or head injury with more than 10 minutes of unconsciousness; hormone disorder; electroconvulsive therapy within 5 years; history of chemotherapy for cancer; current pregnancy; contraindications to MRI

Study details
    Neurobehavioral Components of Reward and Loss Valuation

NCT05384158

Virginia Polytechnic Institute and State University

27 January 2024

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