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Second Window Indocyanine Green for All Nervous System Tumors

Second Window Indocyanine Green for All Nervous System Tumors

Non Recruiting
18 years and older
All
Phase 1

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Overview

The study is being conducted to determine if a same-day, low-dose intravenous (into a vein) injection of indocyanine green (ICG) (FDA-approved dye) being detected by using an imaging system can be a useful tool in identifying and differentiating tumor tissue from normal tissues.

Eligibility

Inclusion Criteria:

  1. Adult patients 18 years of age and older
  2. Patients presenting with a nervous system tumor presumed to be resectable and at risk for local recurrence on pre-operative assessment
  3. Good operative candidates, as determined by the treating physician and multidisciplinary team
  4. Subjects capable of giving informed consent

Exclusion Criteria:

  1. Pregnant women, as determined by urinary or serum beta hCG within 48 hours of surgery
  2. Subjects with a history of iodide allergies
  3. Vulnerable patient populations
  4. Patients unable to participate in the consent process
  5. Patients with history of uncontrolled HTN (requiring ER admission or ≥ 3 BP medications)

Study details
    Nervous System Tumor

NCT05746104

Abramson Cancer Center at Penn Medicine

20 August 2025

FAQs

Learn more about clinical trials

What is a clinical trial?

A clinical trial is a study designed to test specific interventions or treatments' effectiveness and safety, paving the way for new, innovative healthcare solutions.

Why should I take part in a clinical trial?

Participating in a clinical trial provides early access to potentially effective treatments and directly contributes to the healthcare advancements that benefit us all.

How long does a clinical trial take place?

The duration of clinical trials varies. Some trials last weeks, some years, depending on the phase and intention of the trial.

Do I get compensated for taking part in clinical trials?

Compensation varies per trial. Some offer payment or reimbursement for time and travel, while others may not.

How safe are clinical trials?

Clinical trials follow strict ethical guidelines and protocols to safeguard participants' health. They are closely monitored and safety reviewed regularly.
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