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Sepsis: From Syndrome to Personalized Care

Sepsis: From Syndrome to Personalized Care

Recruiting
18 years and older
All
Phase N/A

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Overview

This is a prospective, observational study designed to examine the performance of biomarkers, molecular biological methods and other analysis in blood from patient with suspected sepsis in the Emergency department, as well as identidying novel sepsis endotypes. Around 1500 patients will be enrolled.

Description

The study will prospectively include adult patients (>18 years) with suspected sepsis admitted to Oslo University Hospital, Ullevål (OUH-Ullevål). Patients admitted to the emergency department and managed by the medical rapid response team or the sepsis rapid response team are considered eligible for inclusion. Informed consent will be collected at the emergency department if possible, or within few days, by a clinical investigator or a study nurse. The investigators aim to include 1500 patients treated by the Sepsis Rapid Response Team or Medical Emergency team for possible sepsis. Patients classified to have had other conditions than sepsis in the post hoc assessment will be used as controls. The inclusion period will be 3 years.

Eligibility

Inclusion Criteria:

  • admitted to emergency department OUH, Ullevål.
  • managed by the medical rapid response team or the sepsis rapid response team

Exclusion Criteria:

  • Not given informed consent by patient or next of kin (if patient is not able to)

Study details
    Sepsis Syndrome
    Sepsis
    Sepsis
    Severe
    Septic Shock

NCT04203979

Oslo University Hospital

27 January 2024

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