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Multiparametric Imaging for Analysis of MVNT (Multinodular and Vacuolating Neuronal Tumor)

Multiparametric Imaging for Analysis of MVNT (Multinodular and Vacuolating Neuronal Tumor)

Not Recruiting
18 years and older
All
Phase N/A

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Overview

Differential diagnoses of MVNT include DNT (dysembryoplastic neuroepithelial tumor), low-grade gliomas, cortical dysplasias or even hamartomas.

Description

Differential diagnoses of MVNT include DNT (dysembryoplastic neuroepithelial tumor), low-grade gliomas, cortical dysplasias or even hamartomas.

However, in order to avoid an invasive surgical procedure to remove the lesion, a certain diagnosis of its benignity is essential. The contribution of advanced techniques in MRI, such as spectroscopy in the characterization of these lesions, has not yet been studied today

Eligibility

Inclusion Criteria:

  • Patient over 18 years old
  • Suspicion of MVNT on an MRI: it is considered that it will be necessary at least the 2 major criteria associated with at least 1 minor criterion to enter the definition of suspicion of MVNT:

Major criteria:

  • Multinodular aspect in cluster
  • High FLAIR hypersignal / T2

Minor criteria:

  • Absence of mass effect
  • Hyposignal T1
  • Center of the lesion in hypsignal FLAIR or T1 hypersignal
    • Affiliate or beneficiary of a Social Security scheme
    • Having received informed information about the study and consenting to participate in the study

Exclusion Criteria:

  • Patient benefiting from a legal protection measure
  • Pregnant or lactating woman
  • Contraindication to MRI

Study details
    Benign Neuronal Desease

NCT04103190

Fondation Ophtalmologique Adolphe de Rothschild

30 January 2026

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