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Association Between Renal and Right Cardiac Functions After Urinary Sodium Depletion Following Cardiac Surgery

Recruiting
18 years of age
Both
Phase N/A

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Overview

Following cardiac surgery, right ventricular function may be altered leading to increase central venous pressure and decrease in renal blood flow. The investigator's standard care includes use of diuretic to avoid interstitial fluid accumulation. The aim of the study is to assess cardiac and renal function before and after depletion by using diuretics

Description

The study will compare cardiac and renal data before and 6 hours after use of diuretic

  • Echocardiographic measure of right function (S wave, TAPSE, ventricle surfaces, inferior vena cava diameter) and left function (LVEF, cardiac output
  • Renal function: cumulative diuresis, creatinine level variation and incidence of acute kidney injury using KDIGO classification (creatinine level>26.5 or diuresis<0.05 ml kg-1 h-1)

Eligibility

Inclusion Criteria:

patient undergoing elective cardiac surgery under cardiopulmonary bypass

Exclusion Criteria:

  • heart transplantation
  • use of vasopressor
  • chronic renal disease (DGF under 30 ml min-1)
  • endocarditis
  • patient under ECLS or CPIA
  • patient under 18-year-old

Study details

Cardiorenal Syndrome

NCT03684876

Centre Hospitalier Universitaire, Amiens

27 January 2024

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