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Analysis of Clinical Characteristics and Study of Diagnostic Markers in Patients With Polycystic Ovary Syndrome

Recruiting
18 - 45 years of age
Female
Phase N/A

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Overview

The investigators collected clinical data and serum samples of patients with polycystic ovary syndrome in this study, used statistical software such as SPSS for data analysis, and used experimental techniques such as ELISA to detect serum samples, aiming to explore the relationship between the body anthropometry, glucose and lipid metabolism, gonadal hormones and body fat distribution in patients with polycystic ovary syndrome and to discovery new biomarkers and promote the realization of more accurate personalized medicine.

Eligibility

Inclusion Criteria:

  • Female aged 18- 45;
  • Meet Rotterdam criteria;

Exclusion Criteria:

  • Women who are pregnant or have a pregnancy plan within six months;
  • Congenital adrenocortical hyperplasia;
  • Hyperprolactinemia;
  • Hyperthyroidism or hypothyroidism;
  • Abnormal liver function (≥ 3 times of the upper limit of normal range);
  • Abnormal renal function (GFR<60ml/min/1.73m2);
  • Adrenal or ovarian tumors secreting androgens;
  • Used contraceptives, metformin, GLP-1RA, pioglitazone and contraceptives in the last 3 month.

Study details

Polycystic Ovary Syndrome

NCT05063383

Shanghai 10th People's Hospital

27 January 2024

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