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CKD-702 Plus Irinotecan in Gastric Cancer

CKD-702 Plus Irinotecan in Gastric Cancer

Recruiting
19 years and older
All
Phase 2
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Overview

CKD-702 is a tetravalent bispecific IgG1 targeting hepatocyte growth factor receptor (MET) and epidermal growth factor receptor (EGFR). The investigators will test a hypothesis that CKD-702 may augment the efficacy of biweekly irinotecan as a 3L or later therapy for gastric cancer overexpressing either MET or EGFR.

Eligibility

Inclusion Criteria:

  • Failed 2 or more lines of chemotherapy
  • Tumor overexpressing either MET or EGFR
  • Measurable lesion

Exclusion Criteria:

  • Prior treatment with anti-MET/EGFR bispecific antibody

Study details
    Gastric Cancer

NCT05750290

National Cancer Center, Korea

27 January 2024

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