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Osimertinib as 1st Line Therapy for Patients With Advanced EGFR Positive Non-Small Cell Lung Cancer

Osimertinib as 1st Line Therapy for Patients With Advanced EGFR Positive Non-Small Cell Lung Cancer

Non Recruiting
18 years and older
All
Phase N/A

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Overview

The present study will evaluate the use of osimertinib as 1st line therapy for patients with advanced EGFR positive non-small cell lung cancer who are treated at Hellenic Cooperative Oncology Group (HeCOG)-affiliated departments of oncology.

Description

This will be an observational, multicentric, retrospective/ prospective analysis of patients with advanced EGFR positive non-small cell lung cancer that receive osimertinib as 1st line therapy. The patient data will be collected at Hellenic Cooperative Oncology Group (HeCOG)-affiliated departments of oncology during scheduled patient clinical visits, from February 2020 for a total period of three years. The biological material obtained from the patients of this analysis will be possibly used in a future translational study as an exploratory analysis.

Eligibility

Inclusion Criteria:

  • men or women of 18 years or older that live in Greece
  • histologically or cytologically confirmed, advanced EGFR positive non-small cell lung cancer
  • untreated patients for advanced NSCLC
  • patients who are expected to receive osimertinib regardless of their enrollment in the study
  • signed written informed consent

Exclusion Criteria:

  • patients with cancer other than NSCLC that require treatment
  • pretreated patients for NSCLC
  • patients that receive or are expected to receive or have received an investigational drug/product/intervention

Study details
    Lung Cancer Non-small Cell Stage IV

NCT05127382

Hellenic Cooperative Oncology Group

20 August 2025

FAQs

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