Overview
Detailed description of immune response and its dynamics in sepsis and septic shock patiens by means of transcriptomics, flow-cytometry and cytokine analysis.
Eligibility
Inclusion Criteria:
- sepsis/septic shock (SEPSIS-3)
- age ≥18
- informed consent
- inclusion within first 24hrs after development/diagnosis of septic shock
Exclusion Criteria:
- disagreement of the patient or legal representative with the entry into the study
- patients with primary or secondary immunodeficiency
- presence of active haematological malignancy or an active non-haematological malignancy