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A Retrospective Assessment of OviTex PRS (OviTex)

A Retrospective Assessment of OviTex PRS (OviTex)

Recruiting
18-70 years
Female
Phase N/A

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Overview

The objective of this retrospective-prospective, observational study is to evaluate the safety profile overall and within two device types of OviTex PRS in previous pre-pectoral or sub-pectoral implant-based breast reconstructions.

Description

This study is organized as a retrospective-prospective, observational, multi-center study. The treatment group involved in the study received OviTex PRS during implant-based breast reconstruction. The reconstruction procedure was an immediate or two-stage unilateral or bilateral implant in either the sub-pectoral or pre-pectoral position. Results from this study are aimed to demonstrate an acceptable safety profile and to inform the study design and effectiveness endpoints of a future prospective study.

Eligibility

Inclusion Criteria:

  1. Patient was between 18 years and 70 years of age (inclusive) at the time of surgery.
  2. At the time of surgery, the patient received an OviTex PRS Permanent (R20143 or R20243) or Resorbable (R20152 or R20252) implant in conjunction with an implant-based breast reconstruction.
  3. Patient is 6-months or more post initial surgical procedure.

Exclusion Criteria:

  1. Patient received a textured expander or implant.
  2. Patient was a nicotine user (including smokeless, vaporized, etc.) within 4-weeks preceeding their index procedure.
  3. Patient was marijuana user (including smokeless, vaporized, etc.) within 4-weeks preceding their index procedure.
  4. Patient had previously undergone radiation therapy to the chest wall prior to index surgery.

Additional prospective inclusion criteria (if applicable):

  1. Patient agrees to return in-person for prospective portion including the completion of photographs.

Additional prospective exclusion criteria (if applicable):

  1. Patient has a history of a psychological condision, drug or alcohol abuse which may interfere with their ability to adhere to the follow-up requirements.

Study details
    Reconstructive Surgical Procedures

NCT05736848

Tela Bio Inc

27 January 2024

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