Overview

NCT/DKFZ/DKTK MASTER is a prospective, continuously recruiting, multicenter observational study for biology-guided stratification of adults with rare cancers, including rare subtypes of common entities, using comprehensive molecular profiling, and clinical decision-making in a multidisciplinary molecular tumor board.

Eligibility

Inclusion Criteria:

        Rare cancer (Incidence <6/100,000 persons/year) or Rare subtype of a more common entity
        (case-by-case decision; example: pancreatic ductal adenocarcinoma without KRAS mutation)
        Metastatic and/or locally advanced cancer with no curative therapy option and indication
        for systemic therapy
        Exclusion Criteria:
        Severe neurological or psychiatric disorder interfering with the ability to give oral and
        written informed consent