Overview
The aim of this study is to investigate therapeutic outcomes of anatomical radiofrequency ablation for peripherally located small hepatocellular carcinoma using combined energy delivery mode and triple cooled-wet electrodes.
Eligibility
Inclusion Criteria:
- Child-Pugh class A or B7.
- Presence of chronic hepatitis B or liver cirrhosis.
- Patients with hepatocellular carcinomas diagnosed by histopathology or noninvasive imaging-based diagnosis according to the Korean Liver Cancer Association-National Cancer Center Korea guidelines.
- Patients with viable hepatocellular carcinoma after locoregional treatment diagnosed by the Liver Imaging Reporting and Data System.
- Tumor location is less than 5 cm from liver capsule.
Exclusion Criteria:
- The number of tumor is three or more.
- Tumor size is over 3 cm.
- Tumor location is over 5 cm from liver capsule.
- Child-Pugh class B8-9 or C.
- Presence of macrovascular invasion and/or distant metastasis.
- Platelet count < 50,000 mm3, or international normalized ratio > 1.5 (prothrombin time >1.5 × normal).