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PRIMO Post-Market Clinical Follow Up Study

Recruiting
18 - 100 years of age
Both
Phase N/A

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Overview

Post Market Clinical Follow up Study aimed to collect clinical data on safety and efficacy of Robotically Assisted System called Symani to perform microsurgery techniques such as anastomosis, suturing and ligation for open surgery procedures on small anatomical structures such as blood vessels, lymphatic ducts and nerves.

Description

PMCF study aimed to monitor the safety, usability, performance and long-term efficacy of Symani. Furthermore, it will permit to detect potential emerging risks related to safety on the basis of clinical evidence through the observation of patients who have undergone microsurgical reconstructions using the Symani Surgical System in the usual setting of standard surgical practice.

Eligibility

Inclusion Criteria:

  • Male and female patients aged >18
  • Patients who need a reconstructive procedure and a microsurgical reconstruction is deemed the best option by the plastic, orthopedic or other surgeon in response to a post-oncological, post-traumatic or congenital tissue defect or to treat lymphedema.
  • Patients who have been selected by the Clinical Registry Manager at the Clinical Center as appropriate candidates for treatment with RASM in accordance with the Instruction For Use (IFU).
  • Subjects who fit the criteria to perform surgery requiring reconstructions using free flaps, replantations or lymphatic reconstructions.
  • Subjects who agree to have the surgery and the anesthesia.
  • Subjects who voluntarily decide to participate in this registry with the surgery performed with the aid of the RASM Surgical System and sign the Informed Consent Form

Exclusion Criteria:

  • Subjects who have bleeding or coagulation disorders in the past or present.
  • Any criteria that preclude prolonged anesthesia.
  • History of anaphylaxis or severe complicated allergy symptoms.
  • Clinically significant cardiovascular, digestive, respiratory, endocrine, or central nervous system disorders or previous mental disorders that may significantly affect the data collection or the ability to comply with the protocol.
  • Evidence or history of autoimmune disease or compromised immune system.
  • Participation in another clinical trial within 4 weeks prior to participation in the registry.
  • Subjects belonging to vulnerable populations or ineligible to participate for other reasons by a Clinical Registry Manager at a Clinical Center.
  • Subjects with pacemaker

Study details

Open Surgery, Blood Vessels, Lymphatic Ducts and Nerves, Free Flaps

NCT04843436

MMI Spa

27 January 2024

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