Overview
Physical frailty and malnutrition are important factors in morbidity and mortality in patients with cirrhosis. No study has assessed the validity of Liver Frailty Index (LFI) against reference measures such as maximal lower limb strength.
Main objective: To assess the association between LFI score and isometric maximal lower limb strength (quadriceps) in patients with cirrhosis.
Eligibility
Inclusion Criteria:
SUBJECT :
- with a diagnosis of liver cirrhosis (regardless of cirrhosis stage and etiology)
- under the care of a physician practising in the University Hospital Estaing in Clermont-Ferrand
- affiliated to the french social security system
Exclusion Criteria:
- SUBJECT
-
- with hepatocellular carcinoma
- with HIV infection
- with hepatic encephalopathy grade ≥ 2
- with cognitive dysfunction
- with contraindication for physical activity
- with knee pain/knee disorders
- pregnant or breastfeeding
- under protective supervision (guardianship, curatorship, protection of the court)