Overview
The purpose of the study is to assess if melatonin given for three nights before wisdom tooth surgery decreases post-operative pain and pain medication consumption. Patients will receive either melatonin or a placebo for three nights prior to surgery and we will measure pre-operative anxiety, preoperative sleep quality, post op pain medication consumption, post op pain scores, and blood values.
Eligibility
Inclusion Criteria:
- Subject must have 3-4 partial or full bony impacted third molars requiring surgical extraction under IV sedation
- Ages 18-35
- ASA Class I or II
- English or Spanish speaking patients
- Capacity to sign informed consent
Exclusion Criteria:
- Allergies to melatonin, opioids, or other OTC pain medications
- Anyone currently taking melatonin for any reason
- Cases under local anesthesia
- ASA class III or higher
- Sleep disorder (insomnia/narcolepsy)
- Current or past history of substance abuse
- Chronic pain
- Language/communication barrier
- Psychiatric disease/ Mental impairment
- Current or past use of psychotropic drugs
- Pregnancy
- Renal or hepatic impairment
- BMI >35