Overview

The purpose of this study is to evaluate the integration of cancer pan-genetic testing into a cancer clinical practice and understand both its use and effect in "real world" practice conditions.

Eligibility

Inclusion Criteria:

• Has Mayo Clinic medical record number,
• Confirmed cancer diagnosis which is either recurrent, relapsed, refractory, metastatic, or advanced,
• Participant aware of cancer diagnosis,
• Able to provide informed consent,
• Ability to provide blood, saliva, bone marrow aspirate or hair follicle sample,
• Ability to provide archived tissue, Note: if tissue unavailable participant may still enroll onto the study for the germline collection.

Exclusion Criteria:

Individuals who have situations that would limit compliance with the study requirements:

• Institutionalized (i.e. Federal Medical Prison),
• Prior germline genetic testing with a 40+ multi-gene panel within the last 1 year of enrollment, AND/OR
• Prior somatic (250+ gene) testing within the prior 3 months of enrollment

Note: Women who are pregnant or planning to become pregnant can take part in this study.