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Effect of Platelet-rich Plasma (PRP) Injection on Knee Osteoarthritis

Effect of Platelet-rich Plasma (PRP) Injection on Knee Osteoarthritis

Recruiting
20-60 years
All
Phase N/A

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Overview

To evaluate the safety and effectiveness of PRP injection therapy in the repair of osteoarthritis and periarticular soft tissue injury through a single-center, exploratory clinical study, and to provide a more reliable basis for the treatment of joint injury.

Eligibility

Inclusion Criteria:

  • The age range of the participants was 20 to 60 years old. Through a comprehensive clinical and imaging examination, it was conclusively determined that the individuals had knee osteoarthritis or experienced injuries to the cart, and meniscus surrounding the knee joint.
  • The preoperative routine tests and examinations revealed no contraindications.
  • Revised sentence: "Informed consent of the patient

Exclusion Criteria:

  • The platelet count or function exhibits significant abnormalities、Systemic infection transmitted through the bloodstream.
  • Prolonged usage of anti-inflammatory drugs and systemic corticoid administration.
  • In injection site or damage to the skin.
  • Patients with tumors or undergoing radiotherapy and chemotherapy.
  • Pregnant or breastfeeding women.
  • Individuals with mental illnesses who are unable to cooperate with follow-up procedures.
  • Contraindications for MRI、Patients or their families do consent to participate in the study.
  • Other circumstances that render participation in the study unsuitable.

Study details
    Platelets-rich Plasma
    Osteoarthritis Knees Both
    Meniscus Disorder
    Cartilage Injury

NCT06082531

Xijing Hospital

27 January 2024

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