Overview
This study will evaluate the efficacy of the a 15% trichloroacetic acid + 3% glycolic acid peel combination for treatment of lentigines on the hands. This peel combination is sold over the counter. Patients will receive 3 treatments (spaced 4 weeks).
Description
This clinical investigation is a prospective study consisting of a screening visit, 3 treatment visits, and 1 follow-up visit. Baseline and post-treatment photos will be graded and compared.
A total of 20 patients will be recruited. Following informed consent and screening, subjects' dorsal hands will be photographed.
Patients will receive 3 treatments with the 15% TCA + 3% glycolic acid peel every 4-6 weeks on the dorsal hands. Post-treatment, patients will be instructed to apply Aquaphor to the treated area twice daily for 5 days. Patients' hands will be photographed at each visit.
Four to six weeks after their final treatment, subjects will return for photography.
Eligibility
Inclusion Criteria:
- Age >21
- No laser, chemical peel, neuromodulator, filler treatment to the hands in >3 months
- At least 5 lentigines on each hand
Exclusion Criteria:
- Pregnancy
- Breastfeeding
- Allergy to trichloroacetic acid
- Allergy to glycolic acid
- Open wounds on treatment area (hands)
- Active inflammatory disease on treatment area such as atopic dermatitis, psoriasis, dermatomyositis