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Genetics of Appendix Cancer Study

Genetics of Appendix Cancer Study

Recruiting
18 years and older
All
Phase N/A

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Overview

The GAP Study is a prospective cohort study designed to comprehensively investigate genetic variations that may contribute to cancer development among individuals diagnosed with appendix/appendiceal cancer who are ages 18+ years.

Description

The Genetics of Appendix Cancer (GAP) Study aims to analyze hereditary factors, tumor characteristics and clinical features/outcomes among adults diagnosed with appendix cancer and their biological parents. Patients are recruited at any time after a diagnosis of appendix cancer and followed for up to 6 years after study enrollment. This cohort is enriched by robust biospecimens and data collections.

Eligibility

Inclusion Criteria:

GAP Social

  • Known diagnosis of appendix cancer in the United States
  • Mentally and physically able to consent and participate in the study

GAP Vanderbilt

  • Known diagnosis of appendix cancer
  • Diagnosed by and/or consulting with a physician/clinical provider participating in the GAP Study
  • Mentally and physically able to consent and participate in the study

GAP Parent

  • Biological parents (mother and/or father) of individuals actively participating in the GAP Study
  • Residing in the United States
  • Mentally and physically able to consent and participate in the study

Exclusion Criteria:

  • Women pregnant at the time of consent
  • Prisoners
  • Unable to provide informed consent
  • Unable to read, write, or complete questionnaires in English

Study details
    Appendix Cancer
    Appendiceal Cancer
    Appendiceal Neoplasms
    Appendiceal Mucinous Neoplasm
    Appendiceal Adenocarcinoma
    Appendiceal Carcinoid Tumor
    Appendiceal Neoplasm Malignant Secondary
    Appendix Adenocarcinoma
    Appendix Mucinous Neoplasm
    Appendix Tumor
    Appendix Cancer Metastatic
    Appendix NET
    Low-Grade Appendix Mucinous Neoplasm
    High Grade Appendix Mucinous Neoplasm
    High Grade Appendix Mucinous Adenocarcinoma

NCT05734430

Andreana Holowatyj, PhD, MSCI

30 April 2025

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FAQs

Learn more about clinical trials

What is a clinical trial?

A clinical trial is a study designed to test specific interventions or treatments' effectiveness and safety, paving the way for new, innovative healthcare solutions.

Why should I take part in a clinical trial?

Participating in a clinical trial provides early access to potentially effective treatments and directly contributes to the healthcare advancements that benefit us all.

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The duration of clinical trials varies. Some trials last weeks, some years, depending on the phase and intention of the trial.

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Compensation varies per trial. Some offer payment or reimbursement for time and travel, while others may not.

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Clinical trials follow strict ethical guidelines and protocols to safeguard participants' health. They are closely monitored and safety reviewed regularly.
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