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Effect of Anticoagulant Drug Intervention on Postoperative MALE and MACE in Patients With PAD

Effect of Anticoagulant Drug Intervention on Postoperative MALE and MACE in Patients With PAD

Recruiting
50 years and older
All
Phase N/A

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Overview

Patients with PAD were grouped according to the combination of different anticoagulant and antiplate drugs. The type, dosage and duration of anticoagulant and antiplatelet drugs were recorded after operation. Major Adverse Cardiovascular Events and Major Adverse Limb Events were followed up at 1 month, 6 months and 12 months, respectively.

Eligibility

Inclusion Criteria:

  1. Age ≥50 years old
  2. Patients with symptomatic PAD
  3. Moderate intermittent claudication, or severe limb ischemia
  4. Radiographically confirmed occlusion
  5. Received a successful revascularization

Exclusion Criteria:

  1. Acute limb ischemia occurred within 2 weeks before revascularization;
  2. Large tissue defect of any lower limb (defined as obvious ulceration/gangrene near phalangeal head);
  3. After revascularization, there are clinical conditions requiring systemic anticoagulation

Study details
    Anticoagulant Drugs
    Antiplatelet Drug
    Peripheral Arterial Disease

NCT05852197

First Affiliated Hospital of Zhejiang University

27 January 2024

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