Overview
This study collects blood and urine samples from patients with bladder cancer to support the development of tests for early detection of bladder cancer.
Description
PRIMARY OBJECTIVE:
I. To establish a biobank of samples (blood and urine) to support the development of non-invasive tests for early detection of bladder cancer.
OUTLINE: This is an observational study.
Patients undergo blood and urine sample collection and have their medical records reviewed while on study.
Eligibility
Inclusion Criteria:
- Age > 18 years
- Patient has undergone office-based evaluation for hematuria (computed tomography [CT], ultrasound, cystoscopy)
Exclusion Criteria:
- Patient has known cancer outside of the target cancer 5 years prior to current collection (not including basal cell or squamous cell skin cancers; if patient has not been seen or if information is not available, the patient is eligible)
- Patient has recurrent muscle invasive bladder cancer
- Patient has ever been previously diagnosed with UTUC (upper tract urothelial carcinoma) prior to bladder resection
- Patient has received chemotherapy class drugs for the treatment of non-target origin cancer in the 5 years prior to current collection
- Patient has had any prior radiation therapy to the target lesion prior to current collection
- Patient has had a biopsy to the target organ and/or lesion within 3 days before collection
- Patient has undergone cystectomy
- Patient has transurethral instrumentation (placement of urinary catheter) within 7 days prior to urine collection
- Patient has had a urinary tract infection within 14 days prior to urine collection
- Patient has chronic indwelling urinary catheter
- Patient has prior diagnosis of bladder cancer for which prior resection of tumor was performed