Overview
The investigator would like to investigate the impact of intermittent theta burst stimulation over bilateral posterior superior temporal sulcus in autism spectrum disorder
Eligibility
Inclusion Criteria:
- Autism spectrum disorder, confirmed by Autism Diagnostic Observation Schedule II (CSS≧6)
- No change in psychiatric drugs within one month
Exclusion Criteria:
- Previous or current severe neurological disorder such as epilepsy, visual or hearing impairment
- Previous or current severe systemic disease such as cardiovascular disease, diabetes or infection
- Previous or current severe brain injury
- Implementation of metal materials such as pacemaker or medication pump
- Previous or current severe psychiatric disorders such as schizophrenia, bipolar disorder or substance abuse
- Pregnancy
- Individuals with a significant brain abnormality such as intracranial space occupied lesions
- History of brain surgery or nervous system infection, such as meningitis and encephalitis
- Previous febrile seizures
- Concurrent use of medications which increased the risk of seizure attack.
- Participate another clinical trial within one month.
- Unable to complete MRI scan (claustrophobia)
- Skin trauma on application site
- Individuals with a large ischemic scar
- Individuals suffering from multiple sclerosis
- Individuals suffering from sleep deprivation during rTMS procedures
- Individuals with a heavy consumption of alcohol
- Individuals with a migraine headache from increased intracranial pressure