Image

Effects of Oral Cancer Treatments on Upper Esophageal Opening During Swallowing

Effects of Oral Cancer Treatments on Upper Esophageal Opening During Swallowing

Non Recruiting
18 years and older
All
Phase N/A

Powered by AI

Overview

The purpose of this study is to investigate post-operative and post-radiation upper esophageal sphincter opening measures in oral cancer patients, compare measures to age- and gender-matched healthy adults, and determine relationships with patient swallowing outcomes and quality of life.

Eligibility

Inclusion Criteria:

  • Oral cancer that includes tongue or floor of mouth clinical stage T1 or higher
  • May have disease that extends to base of tongue or other site as long as floor of mouth or tongue are involved
  • Adults at least 18 years of age

Exclusion Criteria:

  • Oral cancer of the lip, cheek, palate or other site not impacting tongue or floor of mouth musculature
  • History of floor of mouth, tongue base, pharyngeal or laryngeal surgical resection
  • History of radiation treatment to the head and neck
  • History of dysphagia prior to onset of oral cancer symptoms
  • Allergy to lidocaine, barium, adhesive tape or apple flavoring
  • Woman of childbearing years who are pregnant

Study details
    Cancer of Head and Neck

NCT04658342

University of Wisconsin, Madison

20 August 2025

FAQs

Learn more about clinical trials

What is a clinical trial?

A clinical trial is a study designed to test specific interventions or treatments' effectiveness and safety, paving the way for new, innovative healthcare solutions.

Why should I take part in a clinical trial?

Participating in a clinical trial provides early access to potentially effective treatments and directly contributes to the healthcare advancements that benefit us all.

How long does a clinical trial take place?

The duration of clinical trials varies. Some trials last weeks, some years, depending on the phase and intention of the trial.

Do I get compensated for taking part in clinical trials?

Compensation varies per trial. Some offer payment or reimbursement for time and travel, while others may not.

How safe are clinical trials?

Clinical trials follow strict ethical guidelines and protocols to safeguard participants' health. They are closely monitored and safety reviewed regularly.
Add a private note
  • abc Select a piece of text.
  • Add notes visible only to you.
  • Send it to people through a passcode protected link.