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Pain, Inflammation and Opioid Craving

Recruiting
18 years of age
Both
Phase N/A

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Overview

The goal of this study is to investigate the association between response to pain and opioid craving in people with opioid use disorder. In this study, adults with opioid use disorder will be randomized to one of two brief education sessions followed by an assessment of response to pain. Investigators will test the association between response to pain and opioid craving.

Eligibility

Inclusion Criteria:

  • age 18 years or older;
  • diagnosis of opioid use disorder
  • chronic pain
  • ability to read and provide informed consent

Exclusion Criteria:

  • major psychiatric or medical condition that would interfere with participation
  • current opioid withdrawal
  • currently receiving opioid analgesic medication for pain
  • recent history of myocardial infarction or other serious cardiovascular condition
  • current peripheral neuropathy, active vasculitis or severe peripheral vascular disease
  • systematic inflammatory or autoimmune disorder
  • admitted to current treatment episode on an involuntary status

Study details

Opioid-use Disorder

NCT04190563

Mclean Hospital

29 January 2024

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FAQs

Learn more about clinical trials

What is a clinical trial?

A clinical trial is a study designed to test specific interventions or treatments' effectiveness and safety, paving the way for new, innovative healthcare solutions.

Why should I take part in a clinical trial?

Participating in a clinical trial provides early access to potentially effective treatments and directly contributes to the healthcare advancements that benefit us all.

How long does a clinical trial take place?

The duration of clinical trials varies. Some trials last weeks, some years, depending on the phase and intention of the trial.

Do I get compensated for taking part in clinical trials?

Compensation varies per trial. Some offer payment or reimbursement for time and travel, while others may not.

How safe are clinical trials?

Clinical trials follow strict ethical guidelines and protocols to safeguard participants' health. They are closely monitored and safety reviewed regularly.
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