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Safety of Pregnant Subjects Exposed to Ibrexafungerp Including Infant Outcomes

Safety of Pregnant Subjects Exposed to Ibrexafungerp Including Infant Outcomes

Recruiting
Female
Phase N/A

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Overview

This is an ongoing evaluation of subjects exposed to ibrexafungerp while pregnant. The study population will include pregnant women of any age.

Description

This is a single-arm safety study which comprises an ongoing evaluation of subjects exposed to ibrexafungerp while pregnant. The study population will include pregnant women of any age who were exposed to ibrexafungerp during pregnancy, or whose conception is estimated to have occurred within four days after receiving last dose of ibrexafungerp, and are volunteering to take part in this study. Subjects will be monitored starting from exposure during pregnancy until one year after live delivery.

Information on pregnancy outcomes and complications as well as fetal/neonatal/infant outcomes will be collected during the timeframe described in the protocol.

Subjects can enroll in the study by calling the telephone number directly (1-888-982-7299) or through SCYNEXIS BREXAFEMME Pregnancy Study Webpage, OR her healthcare provider (HCP) can, with her consent, enroll her on her behalf.

Data will be collected both retrospectively and prospectively using a variety of questionnaire that will be completed by the representative based on interview with the subject and/or HCP

Eligibility

Inclusion Criteria:

  1. Exposure to ibrexafungerp during pregnancy or if conception is estimated to have occurred within 4 days of the last dose of ibrexafungerp
  2. Subject and/or parent/legal representative consents to participate and agrees to the conditions and requirements of the study including the interview schedule/completion of questionnaire and release of medical records
    • Subject can be identified by the sponsor or HCP, in terms of confirmed pregnancy.
        A self-reported pregnancy will be considered as confirmed pregnancy if the Urine Pregnancy
        Test (UPT) result is positive.
          -  A woman can self-enroll in the study or her healthcare provider (HCP), with her
             consent, can enroll her on her behalf.
        Exclusion Criteria:
          1. Females who were not exposed to safety study medications during pregnancy
          2. Refusal to participate in the study
          3. An inability to provide an accurate medical history or give informed consent

Study details
    Vulvovaginal Candidiasis
    Candida Infection
    Vaginal Candidiasis

NCT05908682

Scynexis, Inc.

26 January 2024

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FAQs

Learn more about clinical trials

What is a clinical trial?

A clinical trial is a study designed to test specific interventions or treatments' effectiveness and safety, paving the way for new, innovative healthcare solutions.

Why should I take part in a clinical trial?

Participating in a clinical trial provides early access to potentially effective treatments and directly contributes to the healthcare advancements that benefit us all.

How long does a clinical trial take place?

The duration of clinical trials varies. Some trials last weeks, some years, depending on the phase and intention of the trial.

Do I get compensated for taking part in clinical trials?

Compensation varies per trial. Some offer payment or reimbursement for time and travel, while others may not.

How safe are clinical trials?

Clinical trials follow strict ethical guidelines and protocols to safeguard participants' health. They are closely monitored and safety reviewed regularly.
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