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The Role of Consolidative Autologous Stem Cell Transplantation After First-line Therapy in Peripheral T Cell Lymphoma

The Role of Consolidative Autologous Stem Cell Transplantation After First-line Therapy in Peripheral T Cell Lymphoma

Recruiting
18-65 years
All
Phase N/A
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Overview

The role of autologous stem cell transplantation (ASCT) in the first remission (CR1 & PR1) of peripheral T-cell lymphomas (PTCLs) is not well defined. This study analyzed the impact of ASCT on the clinical outcomes of patients with newly diagnosed PTCL in CR1 and PR1.

Eligibility

Inclusion Criteria:

  • Patients with confirmed pathological diagnosis of aggressive PTCL
  • Age 18-65 years old
  • Achieving CR or PR after first-line therapy

Exclusion Criteria:

  • Subtypes with a more indolent course, including precursor T/natural killer neoplasms, T-cell large granular lymphocytic leukemia, mycosis fungoides other than transformed mycosis fungoides, Sézary syndrome, and primary cutaneous CD30-positive disorders.

Study details
    Peripheral T Cell Lymphoma

NCT04489264

Peking University

26 January 2024

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