Overview

This study is a 4-year randomized, controlled trial comparing cognitive behavioral therapy (CBT) to usual clinical care for children (aged 6-14 years) with autism and emotional dysregulation (e.g., irritability, anxiety). We will randomly assign 50 mental health clinicians, each treating 2 youth (N = 100 youth total), to CBT program for emotional dysregulation and core autism symptoms with weekly live consultation with an expert or to usual clinical care augmented by self-instruction in CBT, in a 1:1 allocation. The CBT manual is well-supported in our efficacy research, has been replicated in other centers, is free/open-access (meya.ucla.edu), and has user-friendly digital and traditional print materials for mental health clinicians (e.g., psychologists, counselors) to use in preparing for and conducting therapy sessions. The primary outcome measure will be assessed weekly. Additional assessments will occur at Screening, Mid-treatment, Post- treatment and 3-month Follow-up.

Eligibility

Clinician's inclusion criteria: All practitioner participants will regularly treat at least

        some youth with ASD within a recognized field of practice (e.g., clinical psychology,
        counseling, marital and family therapy, social work) and will serve youth with ASD referred
        by the Regional Centers, Tricare/NMCSD, or the California public schools. Practitioners
        will agree to invite one or more potentially eligible families of youth with ASD so that,
        in total, at least 2 of the new families referred to them participate in the study (i.e.,
        each clinician will aim to have a cluster of two families randomized to the same condition
        with them; however, the two referrals can be non-parallel and clinicians will not be
        required to enroll a second client to remain in the study, since there is no way for them
        to guarantee future enrollment from client families. As needed, additional clinicians can
        be enrolled in the study to reach the target of 100 youth.). Up to four families per
        practitioner will be allowed so long as the minimum study enrollment of at least 50
        practitioners and 100 client families randomized is met.
        Youth inclusion criteria: Youth participants will be boys or girls between 6 and 14 years
        of age with a documented clinical diagnosis of ASD and will be newly referred for
        outpatient services with a participating clinician. Additional eligibility criteria are as
        follows:
          1. Youth will have a pre-existing clinical diagnosis of ASD made by an appropriate
             licensed professional (e.g., clinical psychologist, developmental pediatrician) which
             will be documented in a report or medical note provided by the family, or confirmed
             telephonically by the diagnosing professional.
          2. The parent-reported Social Responsive Scale-2 (SRS-2; Constantino & Gruber, 2012)
             Total T-Score will be > 60 (cut-score maximizing ROC curve parameters for screening
             for ASD; area under the curve = 98.8%; Schanding et al., 2011).
          3. Youth will meet criteria for clinically significant emotion dysregulation symptoms as
             defined by a minimum T-score of 60 on the Externalizing or Internalizing subscales of
             the parent-reported Brief Problem Monitor (BPM) and at least 15 T-score points over 50
             between these two BPM subscales (e.g., Internalizing=60 + Externalizing=55).
          4. The youth has a Vineland Adaptive Behavior Scales-3 Communication Composite Standard
             Score > 60 and Expressive Communication subscale v-score > 8 (in both cases > 1st
             %ile).
        Exclusion Criteria:
        1. For participants presenting with severe comorbid symptomology (e.g., psychotic
        symptoms), the comorbid conditions cannot be sufficiently severe to warrant immediate
        treatment or require ongoing medication titration.