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An Informational and Supportive Care Intervention for Patients With Locally Advanced Rectal Cancer

An Informational and Supportive Care Intervention for Patients With Locally Advanced Rectal Cancer

Recruiting
18 years and older
All
Phase N/A

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Overview

The aim of this study is to evaluate the efficacy of a brief psychoeducational intervention to improve the self-efficacy of patients with locally advanced rectal cancer who are initiating multimodality treatment (e.g., total neoadjuvant therapy).

Description

This is a randomized control trial that will be split into two phases. Study Phase I will test the feasibility and acceptability of a study evaluating a psychoeducational intervention relative to a control condition for improving self-efficacy in patients with locally advanced rectal cancer who are initiating multimodality treatment. It is expected that this phase will enroll 20 participants. Study Phase II will test the efficacy of the psychoeducational intervention after it has been refined using findings from Study Phase I. It is expected this phase will enroll 100 participants.

In this study, participants will complete survey questions and will be randomly assigned to either receive the intervention (consisting of 4 coaching sessions with a study clinician, a comprehensive patient education guidebook, and a coaching session workbook) or enhanced usual care (consisting of an information resource guide for navigating information online).

It is expected that about 120 people will take part in this research study.

Eligibility

Inclusion Criteria:

  1. Age≄18 years
  2. Within 4 weeks after documented decision to pursue multi-modality therapy for newly diagnosed LARC (i.e., stage II or III disease)
  3. Able to complete study procedures English or with the assistance of an interpreter

Exclusion Criteria:

  1. Comorbid health condition that would interfere with study participation, as identified by cancer care team
  2. Has undergone treatment for a prior colorectal cancer

Study details
    Rectal Cancer
    Self Efficacy

NCT05914766

Massachusetts General Hospital

26 January 2024

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