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The Proportion of Dietary Protein Digested as Measured by the Dual-isotope Method.

The Proportion of Dietary Protein Digested as Measured by the Dual-isotope Method.

Recruiting
65 years and older
All
Phase N/A

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Overview

The retrospective cohort study will compare the prevalence of sarcopenia and associated factors between older patients who have undergone bariatric surgery and older patients with obesity without previous bariatric surgery.

Description

The aim of the study is to compare the prevalence of sarcopenia and nutritional status between adults older than 65 years who have previously undergone bariatric surgery and patients with obesity but without previous bariatric surgery. Current sarcopenia will be assessed during a cross-sectional assessment after surgery using the criteria from the European Working Group on Sarcopenia in Older People (EWGSOP).

Eligibility

Inclusion Criteria:

  • Signed informed consent
  • Age 65 years or older
  • Group 1 & 2: Previous bariatric surgery for obesity 1 - 10 years ago
  • Group 3: No previous weight loss surgery

Exclusion Criteria:

  • Current diagnosis of cancer
  • Advanced organ failure, including chronic kidney disease Stage 5, liver cirrhosis Stage 3, intestinal failure, heart failure stage D, or chronic obstructive pulmonary disease stage 4.
  • Immobility
  • Neuromuscular degenerative conditions
  • Gastrointestinal conditions including coeliac disease, Crohn's disease, previous resection of the small intestine, gastroparesis
  • Unable to follow the procedures of the studies due to cognitive impairment such as diagnosed dementia.
  • Allergy/intolerance to milk, or soy or spirulina

Study details
    Overweight and Obesity
    Bariatric Surgery Candidate
    Aging
    Protein Malabsorption

NCT06076187

Universitaire Ziekenhuizen KU Leuven

26 January 2024

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