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Programmed Intermittent Bolus During Continuous Interscalene Nerve Block for Shoulder Arthroplasty

Programmed Intermittent Bolus During Continuous Interscalene Nerve Block for Shoulder Arthroplasty

Recruiting
18 years and older
All
Phase N/A

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Overview

A new infusion strategy named the 'programmed intermittent bolus' (PIB) technique delivers the hourly dose within minutes compared to the traditional infusion that delivers such dose over an hour. The PIB technique has demonstrated superior patient satisfaction and reduced local anesthetic consumption when utilized for pain control during labour and delivery. However, it is not known if the PIB technique gives any benefits during a continuous nerve block in other settings. The aim of this randomized controlled trial (RCT) is to elucidate if PIB is better than (traditional) continuous infusion for postoperative analgesia in patients receiving a continuous nerve block for total shoulder arthroplasty with respect to pain control.

Description

Local anesthetics are often given in a continuous fashion to block specific nerves after an operation for pain control. A new infusion strategy named the 'programmed intermittent bolus' (PIB) technique delivers the hourly dose within minutes compared to the traditional infusion that delivers such dose over an hour. The PIB technique has demonstrated superior patient satisfaction and reduced local anesthetic consumption when utilized for pain control during labour and delivery. However, it is not known if the PIB technique gives any benefits during a continuous nerve block in other settings. The aim of this randomized controlled trial (RCT) is to elucidate if PIB is better than (traditional) continuous infusion for postoperative analgesia in patients receiving a continuous nerve block for total shoulder arthroplasty with respect to pain control.

Eligibility

Inclusion Criteria:

  • Adult patients
  • American Society of Anesthesiologists (ASA) Physical Status I to III

Exclusion Criteria:

  • Body mass index (BMI) > 40
  • Not able to communicate in ENglish
  • Unable to obtain consent
  • Infection over site of placement
  • Severe respiratory disease
  • Cognitive or psychiatric history that would make it difficult to assess pain score
  • Complex regional pain syndrome
  • Chronic pain condition such as fibromyalgia, neuropathic pain
  • Preoperative opioid use greater than the equivalent of morphine 50 mg PO daily
  • Allergy to any of the study drug
  • Coagulopathy

Study details
    Shoulder Arthroplasty
    Shoulder Osteoarthritis
    Pain Management

NCT03268837

Lawson Health Research Institute

26 January 2024

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