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Familial Pancreatic Cancer PROPHilation Program in Italy

Familial Pancreatic Cancer PROPHilation Program in Italy

Recruiting
18-80 years
All
Phase N/A
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Overview

The goal of the PROPH-ITA Study is to perform genetic testing in family members of pancreatic cancer patients who may have a genetic predisposition. The subjects belong to the Italian Registry of Families At Risk of Pancreatic Cancer (IRFARPC, #NCT04095195). This investigational study will assess the genetic background of subjects with familiarity with pancreatic cancer only.

Participants may accept to undergo genetic testing as part of the IRFARPC registry, through a saliva-swab-based 41-gene panel test.

Up to 3,000 participants will be enrolled in this study.

Eligibility

Inclusion Criteria:

  • Being enrolled on the IRFARPC registry
  • Having familiarity for pancreatic cancer (according to the IRFARPC criteria, Capurso et al. Dig Liv Dis, 2020)
  • Willingness to participate in saliva-swab-based genetic testing

Exclusion Criteria:

  • Already known genetic mutation

Study details
    Candidates for Hereditary Pancreatic Cancer Testing

NCT05724992

Associazione Italiana per lo Studio del Pancreas

26 January 2024

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