Image

Accelerated Recovery After MIS Hepatectomy (ARAMIS Hep) to Support Early Discharge for Patients Undergoing Minimally Invasive Liver Resection

Accelerated Recovery After MIS Hepatectomy (ARAMIS Hep) to Support Early Discharge for Patients Undergoing Minimally Invasive Liver Resection

Recruiting
18 years and older
All
Phase N/A

Powered by AI

Overview

To learn if an accelerated recovery program can shorten the length of hospital stay in patients having minimally invasive liver surgery.

Description

Primary Objectives:

Our study will investigate the feasibility of an accelerated recovery program to minimize length of stay (LOS) and facilitate outpatient surgery for patients undergoing minimally invasive, lower complexity (Kawaguchi-Gayet grade I) liver resection. This program (ARAMIS Hep) will combine minimally invasive surgical (MIS) approaches (robotic OR laparoscopic), enhanced recovery after surgery (ERAS) protocols, and Telehealth to liberalize discharge criteria in a safe manner.

Secondary Objectives:

In addition to demonstrating a reduction in LOS, our study will also provide preliminary data to aid in the broader implementation of this approach. Specifically, we will gain insight into the patient experience, measure patient-reported outcomes on recovery trajectories, and understand barriers to integrating a novel pathway into existing institutional frameworks.

Eligibility

Inclusion Criteria:

  • Tumor amenable to MIS Kawaguchi-Gayet grade I hepatectomy (see figure 1 below)
  • No evidence of cirrhosis (based on imaging, evidence of portal hypertension, clinical features, or laboratory results)
  • No significant cardiopulmonary disease that would prevent patients from undergoing MIS resection
  • Ability to stay within 50 miles of medical center for immediate postop period
  • Age of 18 years or above - because no adverse event data are currently available on enhanced recovery and early discharge after hepatic resection for patients <18 years of age, children are excluded from this study
  • Ability to understand and the willingness to sign a written informed consent document
  • Non-English-speaking patients are eligible for participation

Exclusion Criteria:

Patients who will be excluded include those with:

  • Tumors NOT amenable to MIS Kawaguchi-Gayet grade I hepatectomy
  • Tumors not amenable to MIS or Robotic-assisted surgical resection
  • Evidence of Cirrhosis on imaging, clinically, or lab testing
  • Inability to stay within 50 miles of the Cancer Center in the immediate post-operative period
  • Age below 18 years
  • Inability to consent for trial/protocol
  • Patients who are pregnant

Study details
    Liver

NCT05879159

M.D. Anderson Cancer Center

1 November 2025

Step 1 Get in touch with the nearest study center
We have submitted the contact information you provided to the research team at {{SITE_NAME}}. A copy of the message has been sent to your email for your records.
Would you like to be notified about other trials? Sign up for Patient Notification Services.
Sign up

Send a message

Enter your contact details to connect with study team

Investigator Avatar

Primary Contact

  Other languages supported:

First name*
Last name*
Email*
Phone number*
Other language

FAQs

Learn more about clinical trials

What is a clinical trial?

A clinical trial is a study designed to test specific interventions or treatments' effectiveness and safety, paving the way for new, innovative healthcare solutions.

Why should I take part in a clinical trial?

Participating in a clinical trial provides early access to potentially effective treatments and directly contributes to the healthcare advancements that benefit us all.

How long does a clinical trial take place?

The duration of clinical trials varies. Some trials last weeks, some years, depending on the phase and intention of the trial.

Do I get compensated for taking part in clinical trials?

Compensation varies per trial. Some offer payment or reimbursement for time and travel, while others may not.

How safe are clinical trials?

Clinical trials follow strict ethical guidelines and protocols to safeguard participants' health. They are closely monitored and safety reviewed regularly.
Add a private note
  • abc Select a piece of text.
  • Add notes visible only to you.
  • Send it to people through a passcode protected link.