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Taste Physiology in Obese Volunteers Before and After Bariatric Surgery

Taste Physiology in Obese Volunteers Before and After Bariatric Surgery

Recruiting
18-55 years
All
Phase N/A
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  • Simplified (AI rewritten)

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Overview

The objective is to investigate neuro-anatomical correlates of gastrointestinal taste stimulation by means of functional MRI before and after bariatric surgery. Intragastric administration of glucose, monosodium glutamate, chloroquine and placebo is followed by functional brain MRI in obese humans before and 3 months after surgery.

Eligibility

Inclusion Criteria:

  • morbidly obese patients (BMI min 35kg/m2) scheduled for bariatric surgery
  • right handed

Exclusion Criteria:

  • cardiovascular disease
  • neurologic/psychiatric disorders

Study details
    Obesity

NCT02902198

University Hospital, Basel, Switzerland

26 January 2024

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