Overview
The goal of this observational study is to learn about epilepsy after a stroke (post-stroke epilepsy). The main questions it aims to answer are:
- What make some patients develop epilepsy after a stroke?
- Does sleep have an impact on the development of post-stroke epilepsy?
Participants will undergo:
- Electroencephalography (EEG)
- Magnetic resonance imaging (MRI)
- Polysomnography (only patients)
Blood tests will also be taken. The patient group will be compared to the healthy controls. Researchers will also look into medical records of stroke patients hospitalized at St. Olavs hospital and collect relevant information.
Description
This study aims to study risk factors and clinical factors which might contribute to the development of post-stroke epilepsy. Researchers will look at the volume and size of the stroke-induced brain lesions and analyze inflammation markers. Patients and controls will undergo EEG and MRI. The correlations between sleep and epilepsy after a stroke will also be investigated through polysomnography. Relevant information about for instance age, comorbidities and NIHSS will be collected. Researchers will also collect relevant information from medical records of stroke patients hospitalized at St. Olavs hospital.
Eligibility
Inclusion Criteria:
- First time stroke patients with capacity to consent, admitted to the stroke unit at St. Olavs hospital.
- Modified Rankin Scale (mRS) ≤ 2 before the stroke
Exclusion Criteria:
- Previous stroke or brain surgery
- Traumatic brain injuries
- Neurodegenerative diseases
- Brain tumors
- Epilepsy before the stroke
- Hydrocephalus
- Aphasia
- Serious psychiatric disorders
- MRI incompatibility and claustrophobia