Overview

Tissue will be procured during a standard of care procedure the patient will already be scheduled to undergo. A one time blood draw will be performed at this time and an optional rectal swab for biome analysis may occur. Follow Up will only consist of chart review to determine date of recurrence, metastases, and/or death

Eligibility

Inclusion Criteria:

• Adults >18 years old at time of consent
• Subject must be capable to giving informed consent or have an acceptable surrogate capable of giving consent on the subject behalf.
• Patients with carcinoma in situ or invasive breast cancer
• Patient must be undergoing one of the following:
  • definitive surgical tumor resection for breast cancer OR
  • placement of a vascular access device as a prelude to neoadjuvant therapy for breast cancer OR
  • neurosurgical resection of a brain metastasis from primary breast cancer.

Exclusion Criteria:

• <18 years old
• Not able to give informed consent and does not have acceptable surrogate capable to giving informed consent.
• Active drug/alcohol dependence or abuse history