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Conventional vs. Video-Assisted Laryngoscopy for Perioperative Endotracheal Intubation

Recruiting
18 years of age
Both
Phase N/A

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Overview

COVALENT is a randomized, controlled, multi-center study that aims to evaluate the clinical routine practice of endotracheal intubation in an operative setting comparing video-assisted laryngoscopy to direct laryngoscopy.

Description

Data on the routine use of video-assisted laryngoscopy in peri-operative intubations are rather inconsistent and ambiguous, in part due to small study populations and non-uniform outcome measures in past trials. Failed or prolonged intubation procedures are a reason for relevant morbidity and mortality. This study aims to determine whether video-assisted laryngoscopy (irrespective of the shape of the blade) is non-inferior to the standard method of direct laryngoscopy with respect to the first-pass success rate. Furthermore, validated tools from the field of human factors will be applied to examine within-team communication and task load during this critical medical procedure.

Eligibility

Inclusion Criteria:

  • Adult, legally competent patients
  • Scheduled for elective, non-cardiac surgical procedure
  • Need for endotracheal intubation as determined during the premedication visit
  • Informed consent
  • Care providers performing the intubation have at least one year of training in anesthesiology and experience in the use of VAL

Exclusion Criteria:

  • Lack of ability to give consent
  • Previous participation in this study
  • Pregnancy
  • Need for fiberoptic intubation
  • Patients scheduled for bariatric surgery
  • Any circumstance that will lead the anesthesiologist(s) in charge to believe that random assignment of a laryngoscopy instrument may compromise patient safety during induction of anesthesia

Study details

Endotracheal Intubation

NCT05228288

Wuerzburg University Hospital

26 January 2024

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