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Cardiogenic Shock Working Group Registry

Recruiting
18 years of age
Both
Phase N/A

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Overview

The Cardiogenic Shock Working Group is a multicenter registry where we collect de-identified clinical variables from the medical records and follow-up phone calls of shock patients from multiple institutions and centralize this data to a single registry for analysis of clinical outcomes.

Description

The Cardiogenic Shock Working Group is an Academic Research Consortium involving multiple medical centers within the United States and includes a multicenter registry for patients with cardiogenic shock. De-identified clinical variables are collected from medical records and follow-up phone calls. There is currently no central database for cardiogenic shock, therefore analysis of cardiogenic shock on a larger scale is limited. A goal of the Cardiogenic Shock Working Group is to create a centralized registry, compiled of data from multiple institutions, to analyze clinical outcomes. The Cardiogenic Shock Working Group Registry will include a retrospective arm, where data is collected during the course of the hospital stay, and a prospective arm, where long-term outcomes will be assessed.

Eligibility

Inclusion Criteria:

  • Patients must have cardiogenic shock.

Cardiogenic shock is defined by at least one of the two categories below:

  1. At least 2 of the following concurrently at any point during the index
    hospitalization
    • Cardiac Index < 2.2
    • PAPI < 1.0
    • Cardiac Power Output ≤ 0.6
    • MAP < 60mmHg or a >30mmHg drop in MAP from baseline
    • SBP < 90mmHg or a >30mmHg drop in SBP from baseline
    • Pulse > 100
  2. Require at least one acute mechanical circulatory support device, vasopressor or

    inotrope to maintain values above the above target.

        Post-cardiotomy patients must meet the inclusion criteria 72 hours after their surgery to
        be included in this registry.

Study details

Cardiogenic Shock

NCT04682483

Tufts Medical Center

26 January 2024

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