Overview
Aim : To assess the ability of healthy subjects and patients with a severe motor disability to voluntary control their attention
Material and Methods:
Population: healthy subjects, patients with brain injury Electroencephalographic study to research attentional modulation during different kind of stimulation (visual, auditory, tactile)
Sudy 1: passive recording.
Study 2: active recording (instruction of attentional control given to the subject).
Study 3: active recording with a feedback obtained after a processing of the brain activity.
Eligibility
Inclusion Criteria:
Inclusion criteria for patients :
- Adults, man or woman, left or right-handed, from 18 years old to 80 years-old ;
- Diagnosis :
- Locked-in syndrome :
< Brainstem injury, without any evolution for at least 3 week, etiology : vascular,
traumatic < Amyotrophic Lateral Sclerosis < Following damage to the central or peripheral
nervous system
- Or Minimal conscious state or Unresponsive Wakefulness Syndrome consecutive to a
severe acquired brain injury for at least one month
- Or with a severe brain injury, since birth or acquired, for at least one month
- Or with Guillain-Barré syndrome
- Subjects affiliated to social security;
- Signature of consent form by the patient or by a relative (family member or "the
trusted person") if obtaining a consent is impossible
Inclusion criteria of Healthy subjects
- Adults, man or woman, left or right-handed, from 18 years old to 80 years-old ;
- Without known auditory impairment
- Subjects able to understand the experimental instructions
- Subjects affiliated to social security;
- Signature of consent form
Exclusion criteria of patients and healthy subjects
- Medical history : psychiatric disorders (except if due to brain injury), neurologic
disorders (except if due to brain injury)
- For healthy subjects : history of brain injury
- Pregnant women or breastfeeding women
- Person under legal protection
- Medico-legal conflicts
- Absence of consent by the subject or the patient or his/her representant