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Semitendinosus Graft as Meniscal Transplant

Semitendinosus Graft as Meniscal Transplant

Recruiting
20-50 years
All
Phase N/A

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Overview

Removal of meniscal tissue is described to result in poor knee function and a significant risk for future development of osteoarthritis. Different implants have been suggested to substitute a removed meniscus. Meniscal allograft transplantation is not widely available due to costs and availability. The semitendinosus tendon is a known graft with biological properties with potential to remodel and revascularize in an intraarticular environment such as anterior cruciate ligament reconstruction. The objective for this study was to investigate whether the semitendinosus tendon graft could function as a meniscal transplant.

Eligibility

Inclusion Criteria:

  • Previous subtotal or total meniscectomy
  • Post meniscectomy symptoms
  • No osteoarthritic changes on radiography more than Ahlbäck 1
  • Knee aligment (hip-knee-angle) +/- 3°
  • No persisting ACL insufficiency

Exclusion Criteria:

  • Difficulty understanding the instructions
  • Current psychiatric diagnosis
  • Smoking

Study details
    Patient Satisfaction
    Graft Failure
    Osteo Arthritis Knee
    ACL
    Meniscus Tear

NCT04753424

Karolinska Institutet

26 January 2024

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