Overview
The aim of the study is to evaluate the efficacy of combinations of different scaffolds (blood clot, platelet rich fibrin, collagen) and sodium hypochlorite concentrations (0.5%- 2.5%) in regenerative endodontics of immature non-vital anterior teeth clinically and radiographically using cone-beam computed tomography.
Description
Patients will be divided randomly into six equal groups (n=8)
- Group I: BC scaffold and 0.5% concentration of NaOCl irrigant solution.
- Group II: BC scaffold and 2.5% concentration of NaOCl irrigant solution.
- Group III: PRF scaffold and 0.5% concentration of NaOCl irrigant solution.
- Group IV: PRF scaffold and 2.5% concentration of NaOCl irrigant solution.
- Group V: Collagen scaffold and 0.5% concentration of NaOCl irrigant solution.
- Group VI: Collagen scaffold and 2.5% concentration of NaOCl irrigant solution.
CBCT image will be obtained for baseline records after placement of the final resin restoration then the patients will be recalled after 6 months and 12 months for evaluating any changes in root length, root canal width, apex diameter and lesion size if present. The success rates for patients at each recall visit will be scored as follows
- Score 0: Persistence of clinical and radiographic findings.
- Score 1: Absence of swelling, drainage and pain along with radiographic evidence of osseous healing + no evidence of increased root dimensions.
- Score 2: Absence of swelling, drainage and pain along with radiographic evidence of osseous healing + radiographic root development.
Eligibility
Inclusion Criteria:
- • Patients, abarantly free from any systemic diseases that may hinder the normal
healing process.
- Maxillary traumatized or cariously exposed immature anterior teeth.
- Clinical signs of pulp necrosis.
- Radiographic evidence of incomplete root development based on an apical opening >1 mm.
Exclusion Criteria:
- • Allergy to medication used in the procedure or any medical conditions that
contraindicate endodontic treatment (eg, acute systemic disease and abnormalities in
host defense).
- Non-restorable tooth.
- Radiographic evidence of root fracture.
- Lack of patient and parent cooperation.
- Teeth with vital pulps and complete root development.
- Presence of periodontal pocket > 4 mm.