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The Effect of Zolpidem on Outcomes Following Lumbar Spine Fusion

The Effect of Zolpidem on Outcomes Following Lumbar Spine Fusion

Recruiting
18-75 years
All
Phase N/A

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Overview

The purpose of this study is to evaluate if peri-operative zolpidem for posterior lumbar spinal fusion improves patient reported outcomes following surgery.

Description

Patients who are undergoing one- to three-level spinal fusion for degenerative lumbar disease will be recruited. They will be randomized to either receive zolpidem or placebo two days preoperatively and five days postoperatively.

Eligibility

Inclusion Criteria:

  • degenerative lumbar disease
  • age of 18-75
  • undergoing open primary one- to three-level lumbar fusion

Exclusion Criteria:

  • currently use a sleep aid nightly
  • diagnosed with insomnia or sleep apnea
  • history of delirium with opiates or zolpidem
  • allergic to opiates or zolpidem
  • had previous lumbar spine surgery
  • undergoing minimally invasive lumbar fusion,
  • undergoing lumbar fusion for fracture, infection, tumor, or an inflammatory spondyloarthropathy

Study details
    Spine Fusion
    Lumbar Spine Degeneration
    Pain
    Postoperative
    Lumbar Spine Spondylosis

NCT05746143

University of Southern California

26 January 2024

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