Overview
This research is being done to find out whether intravenous magnesium is effective in the treatment of bladder spasms after urologic surgery.
Eligibility
Inclusion Criteria:
- Be undergoing a bladder invasive procedure with or without planned urinary catheter on Mayo Clinic Gonda 7 Outpatient Procedure Center.
Exclusion Criteria:
- Are unable to grant informed consent or comply with study procedure.
- Allergy or known sensitivity to magnesium or Renacidin.
- Expected or high risk of bladder extravasation.
- Ongoing atrial fibrillation prior to surgery.
- Are undergoing emergency surgery.
- Are pregnant.
- Known hypermagnesemia.
- Patients with neuromuscular weakness (e.g., Myasthenia gravis) due to magnesium's muscle weakening effect.
- Patients with myocardial compromise or cardiac conduction defects because of magnesium's anti-inotropic effects.
- Patients with renal insufficiency, glomerular filtration rate less than 30, since Magnesium is eliminated by the kidneys resulting in exaggerated rise in serum magnesium.
- Patients with concomitant use of a calcium channel blocker since magnesium sulfate could act synergistically to suppress muscular contractility.