Overview
The risk of Arterial Hypertension (HTA) is increased in very premature infants and hydrocortisone administered in the neonatal period could modify this risk.
The main objective is to assess whether the administration of hydrocortisone in the perinatal period in children born prematurely is associated with an increase in Pulse Wave Velocity (PWV) by comparing the future of children included in the PREMILOC trial (hydrocortisone versus placebo) at the age of 7-13 years. The primary endpoint will be the carotid-femoral pulse wave velocity in m/s.
Description
Descriptive cross-sectional study of the subjects included in the double-blind, monocentric randomized controlled trial (children included and followed up at the Robert Debré hospital in the PREMILOC trial): follow-up of these children approximately 10 years later on vascular parameters.
Eligibility
Inclusion Criteria:
- Child included in the PREMILOC trial on the Robert Debré site
- Age from 7 to 13 years old (eve of 14 years old)
- Consent of the holders of parental authority and agreement of the child
Exclusion Criteria:
- Absence of affiliation to a social security scheme
- Patient under state medical aid