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Ultrasound-guided Radiofrequency Ablation of the Genicular Nerve Versus Physical Therapy for Chronic Knee Osteoarthritis

Ultrasound-guided Radiofrequency Ablation of the Genicular Nerve Versus Physical Therapy for Chronic Knee Osteoarthritis

Not Recruiting
45-70 years
All
Phase N/A

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Overview

The aim of this study is to compare the effects of conventional physiotherapy methods with ultrasound-guided radiofrequency ablation of the genicular nerve on pain and functional status in patients with stage 2-3 chronic knee osteoarthritis.

Description

Patients diagnosed with Chronic Knee Osteoarthritis according to the American College of Rheumatology criteria, and with radiological osteoarthritis at Kellgren-Lawrence grades 2 and 3, within the age range of 45-70, and meeting the study criteria will be included in the study. After providing information about the procedures to be performed and potential risks to the patients, if they give their written informed consent, treatment methods will be applied to the patients. Eligible patients will be divided into two groups. In one group, Radiofrequency Ablation of the Genicular Nerve under Ultrasound Guidance will be performed, while the other group will receive physical therapy.

Eligibility

Inclusion Criteria:

  • VAS ≥ 5
  • To be aged between 45 and 70 years old
  • Patients diagnosed with chronic knee osteoarthritis using the American College of Rheumatology criteria and having radiological osteoarthritis of Kellgren-Lawrence grade 2 and 3
  • Cognitive functions being intact
  • Being willing to participate in the study and signing the consent forms

Exclusion Criteria:

  • Having received physical therapy for chronic knee osteoarthritis in the last 6 months
  • Having received glucocorticoid or hyaluronic acid injections in the last 6 months
  • Having taken oral glucosamine
  • Undergoing knee surgery
  • Having current neurological or mental disorders
  • History of pacemaker usage
  • Presence of local infections or sepsis
  • Progressive neurological deficit
  • Presence of oncological diseases
  • Hemorrhagic diathesis or anticoagulation
  • Uncontrolled diabetes or other serious internal comorbidities
  • Allergy to medications or materials used
  • Pregnancy
  • Lack of cooperation
  • Not willing to participate in the study.

Study details
    Chronic Knee Osteoarthritis

NCT06173830

Ankara City Hospital Bilkent

30 January 2026

FAQs

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